How Linear Regression Methods Can Be Used in Biotechnology


Biotechnology is among the fastest developing industries today. Cutting-edge technologies such as machine learning and artificial intelligence are widely used for drug design and bioprocessing. In order to predict the biological activity of new chemical substances, regression analysis and other algorithms are being used. Today we will talk about linear regression and how it helps to create better medicine.

What is linear regression?


Linear regression is a technique of statistical analysis that can be used to model linear relationships between two variables. In case there are more variables or the relationship doesn’t fit a linear equation, other regression methods can be used.

In biotechnology, linear regression allows you to investigate the relationship between molecular structure and the bioactivity of compounds.

It enables you to discover how the change in the biological properties influences the molecule’s biological activities. Check this domain to learn more about the method of linear regression and how it is used.

Multiple linear regression vs linear regression: what’s the difference


Multiple regression is an extension of linear regression. It can operate with a greater number of dependent variables than just one. Multivariate data processing is widely used in bioprocessing. Such algorithms give biotech companies an opportunity to dive deeper into complex data and get more informative insights.

Multiple regression is used to assist in the interpretation of clinical trial data, monitoring of the processes such as fermentation reactions and, generally, provides a much more comprehensive approach to data analysis than simple linear regression.
Multiple linear regression in bioinformatics relies on two steps. First is centered clumping, which involves the extraction of information from each gene prediction run.

The second is custom alignment to the low-hanging fruit of the predictions and selecting the best set of genes to use in further analysis. A key consideration when using ML to perform these two steps is the precision with which the predictor is updated given uncertainties in gene location or actual genetic structure. This constancy in updating can lead to an improved model’s predictive power for high-confidence locations even when gene conversion might occur at low rates.

Advantages of linear regression for biotechnology


Linear regression is simple to use. When you only have historical data and you want to see the correlation between the events, this is the technique that you should choose. Additionally, it allows you to visualize the data points on the scatterplot which helps with the interpretation of the results. You don’t have to create a linear regression model from scratch. There are many ML libraries and automated online tools available that enable you to work with LR.

How to use linear regression in biotechnology?


This section describes the use of ML in biotech. Bio-engineering encompasses all stages of synthetic biology: genome engineering, plasma engineering, transcriptional editing, etc. In this subject, linear regression is used as a base classification system. Biology is very different from computer science, but the two fields are fundamentally related.

It is indeed a very neat coincidence that one of the most important technologies in modern biology has occurred to be in the same area as the programming language ML. Biologists have been using linear regression to calculate nonparametric measures of linear model parameters like the parameters of evolution with respect to time, in a very similar way than that in which one might do this for a game

AI. In bioinformatics, multiple linear regression (MLR) is a powerful software tool that is central to many bioinformatics algorithms. MLR is used to analyze sequences, or nucleotide topology, using maximum likelihood techniques. Actually, linear regression is just one of many techniques used in biotechnology.

Here are the tasks that linear regression can help to solve in biotech:

  • Discover new biologically active substances and medicine;
  • Create microbiological plant protection products against diseases and pests;
  • Develop valuable feed additives and biologically active substances;
  • Uncover new methods of bioengineering for effective prevention, diagnosis, and treatment of major diseases;
  • Help with the processing of agricultural, industrial, and household waste.

All in all, linear regression analysis is mostly used for predictive analysis and risk assessment connected with the development of new medical preparation and substances.


The biotechnology industry is one of the largest & most influential industries in the world. In spite of that fact, the whole power of this science is yet to be fully explored. There are still many obstacles to be overcome, and most biotech companies still lack advanced AI tooling.

Top biotechnology services providers that implement linear regression benefit from operational efficiency, reduced costs, and improved product quality. Linear regression is a simple and reliable tool for statistical analysis. It helps to model a linear relationship between two variables that can be useful in medical discovery and gene editing. In biotechnology, it is usually used as one but not the only technique for predictive analysis and risk assessment.

Machine learning technologies have opened up a new frontier of big data science that is revolutionising the world of biotechnology. ML allows scientists to design complex predictive models much more quickly than through conventional approaches and in doing so can transform the way we look at solving real world biomed problems. Using machine learning algorithms in drug discovery, we can now develop life-saving drugs based on your specific DNA. It’s like having your own personal biotechnology company that’s constantly working to protect your health and improve your longevity.

Some advances in biotech are the result of new technology, but most of the value derives from the collective creativity of a team. The team that comes together to build a biotech project advances the welfare of patients because they are able to accomplish complex goals using computer technology and new data analysis techniques. The team is led by an ML specialist who focuses on data science and innovation. While the technology might not change, the way an industry uses ML will continue to gain momentum, since it allows for more efficient solutions.